What is Hormone Replacement Therapy? (HRT)

Hormone Replacement Therapy is the combination of medical science, biotechnology and life conditioning protocols, Hormone Replacement Therapy (HRT) is one of the most innovative treatments available today is, this is the process by which vital hormones are replaced in a prescribed schedule to mimic the body’s natural process.

What is Hormone Replacement Treatment?

HRT is primarily comprised of two essential elements, Human Growth Hormone (HGH) and Testosterone the combination of this natural hormone and steroid produced by the human body is the key to development, performance and wellness. Aging is the most evident sign that these essential elements are decreasing production in the body and causing many of the radical changes in our appearance and every day activities. Some of the most evident changes are weight gain; low energy, low sex drive, decreasing memory, irritability and muscle wasting are just a few signs of aging.

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Natural HRT

Hormone Replacement Therapy, or HRT, is available and beneficial to both men and women. It is the process of replacing necessary hormones that the body may not be producing well enough on its own. Natural HRT provides the body with the hormones needed during various stages during a person’s life. The information on these pages was created to help you understand Natural Hormone Replacement Therapy and its benefits.

Natural HRT restores the exact hormones that the human body produces during times when it is needed. Many doctors are unaware of natural HRT benefits. These substances are available and bio-identical plant-derived estrogen and progesterone have been safely prescribed in Europe for more than 50 years. Human Growth Hormone, is similar to the hormones Estrogen & Testosterone. There is an expected age related decline in the natural production of all 3 of these vital hormones after the age of 30 in many adult men and women.

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Pituitary Gland

Human Growth Hormone: A natural protein hormone made up of 191 amino acids. Human Growth Hormone (HGH) is the most abundant hormone produced by one of the endocrine glands: the pituitary gland. This gland is located in the center of the brain. HGH is also a very complex hormone. It is made up of 191 amino acids – making it fairly large for a hormone. In fact, it is the largest protein created by the pituitary gland.

Peak HGH Production

HGH secretion reaches its peak in the body during adolescence. This makes sense because bio-identical hormones helps stimulate our body to grow. But, growth hormones secretion does not stop after adolescence. Our body continue to produce growth hormones usually in short bursts during deep sleep.

Aging Effects on HGH

As we get older our body produces less amounts of growth hormone. Human Growth Agent is designed to help your body naturally increase it’s own levels of HGH. Increased levels of growth hormones can assist in weight loss and muscle gain. HGH can also increase your energy level and may assist sexual performance and endurance.

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Human Growth Hormone is known to be critical for tissue repair, muscle growth, healing, brain function, physical and mental health, bone strength, energy and metabolism. In short, it is very important to just about every aspect of our life!

HGH Deficiency

Human Growth Hormone Therapy: Human growth hormone deficiency (GHD) is determined by the measurement of GH levels, and/or height less than the third percentile for the chronologic age for children.

The growth hormone (GH) secretion rate decreases by an estimated 14% per decade after young adulthood. Mean levels in older adults are less than half those of a young adult. However, in older adults, mean GH levels are greater than those of age-matched adults with diagnosed growth hormone deficiency.

HGH Treatment

Recombinant GH is a category of pharmaceutical agents used to treat GHD. Treatment involves administration of subcutaneous GH injections. The dosage is calculated based on the individual’s weight. The injections may be prescribed three to seven times per week. The individual or family member, trained in subcutaneous injections, can administer the therapy.

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Testosterone what is it?

Testosterone: A “male hormone” — a sex hormone produced by the testes that encourages the development of male sexual characteristics, stimulates the activity of the male secondary sex characteristics. Testosterone is the most potent of the naturally occurring androgens. The androgens cause the development of male sex characteristics, such as a deep voice and hair growth; they also strengthen muscle tone and bone mass.

Testosterone Replacement Therapy: Testosterone is necessary only if testosterone (T) levels are below normal. There are two forms of testosterone in the human body. The Total or bound testosterone level (TT) and the Free Testosterone (FT). Free T levels can be detected by salivary testing. Over 75% of the T in saliva is in the FT form. FT drives the normal sex drive in both men and women.

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Female Specific Hormone Replacement Therapy

The principle of traditional HRT is to supply women with hormones when their own hormone production is depleted. By this means short-term symptoms of the menopause, such as hot flashes, night sweats and vaginal dryness may be controlled, and the long-term risks of osteoporosis, cardio-vascular disease and mental deterioration reduced.
Estrogen Replacement Therapy (ERT) was first given for women at the menopause in the 1930s by intra-muscular injection. Implanted pellets of estrogen were used from 1938. But by the 1970s it was becoming clear that there were increased rates of breast and uterine cancer were occurring from estrogens taken on their own (‘unopposed’), and the popularity of ERT waned.

The term Hormone Replacement Therapy (HRT) was used after progesterone-like substances were successfully synthesised in the laboratory and marketed as ‘progestagens’. These progesterone-like substances enabled replacement therapy to follow more closely the pattern of hormone production in premenopausal women. When added to oestrogen therapy for the second half of the monthly cycle progestagens counteract the unopposed action of oestrogens on the uterus, thereby regularising the menstrual cycle and reducing the risk of uterine cancer. Because the risk of uterine cancer is the justification for using progestagens they are not considered necessary if a woman has had a hysterectomy

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There are various ways that traditional HRT is taken: tablets, implants, skin patches, creams, vaginal pessaries, and gels.


Estrogens and progestagens are commonly given in combination, either as Cyclical Sequential therapy or Continuous therapy:

Cyclical Sequential therapy: In this form of treatment estrogens are given from day 1 to 21 and progestagen from day 9 to 21. There are seven days without medication during which time withdrawal bleeding occurs.

Continuous therapy: estrogen is given continuously and progestagens are added from the 14th to 25th day of the cycle. A withdrawal bleed, very similar to a period, occurs within two days of the progestagen being stopped. For convenience progestagens may be taken only at the end of three months so that the frequency of withdrawal bleeding is reduced. Continuous therapy maybe given using Tibolone (Livial), once the lining of the uterus has become non-secretory (about a year after finishing periods).


Up to six month’s supply of estrogen can be given as a sub-cutaneous implant, usually into the abdominal wall. Absorption occurs directly into the blood-stream avoiding the potential hazards of passing through the liver. The dose of oestrogen is smaller but progesterone is still needed to avoid the effects of unopposed oestrogens. However, the dose can’t be varied once the implant is inserted and removal is difficult. Increasing doses may be needed to limit menopausal symptoms for reasons that are not clear.

Skin Patches

Oestrogen is contained in a patch, which is placed on the lower trunk and changed every three or four days. Progestagens are taken from the 14th to the 25th day either as a pill, or by means of a patch combining oestrogen and progestagen. The skin may become red and sore following the use of a patch. With patches of this type the oestrogen is contained in a reservoir of alcohol, which looks like a small bubble, against the skin.

A new Matrix-patch in which estrogen is impregnated in a sponge-like medium is more comfortable, less bulky, and lies flat against the skin.

Creams and Pessaries

Estrogen cream is placed in the vagina with an applicator for the treatment of vaginal symptoms. Only limited absorption of estrogen occurs making it unsuitable as a way of treating other menopausal symptoms.

Estrogen gel provides an effective alternative to the patch. The gel is used on the inner aspect of the upper thigh and rubbed in daily. The dose is adjusted according to individual need on the basis of oestrogen levels measured in blood or saliva.

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Male Testosterone Therapy

Testosterone: Testosterone replacement for men has been available for at least fifty years using injections of material from animal sources. Synthesis of pure hormone has provided greater availability and safety. testosterone can be prescribed in several varieties of testosterone replacement (differing forms and differing routes of application) to several hundred men with depleted hormone levels since 1995. There is increasing professional recognition of its efficacy provided that precautions relating to its possible association with prostate cancer are observed. For this reason, treatment should only be undertaken with medical supervision.

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Let me restate the principles on which testosterone and other male (androgenic) replacement therapy is based.


Reduced testosterone production within some men, an increase in sex hormone binding globulin and aromatisation (conversion) to *estradiol, lead to symptoms of the male menopause or andropause. These symptoms vary widely but include a reduction in well-being, energy and sex-drive, hot flashes and joint pain. There is increased visceral fat (and abdominal girth) and loss of muscle bulk (somatic and cardiac) leading to reduced physical strength and endurance.

Prostate Enlargement

Benign enlargement of the inner core of the prostate gland, giving rise to urinary flow problems, are common in older men. The association of this with testosterone is unclear, and dietary factors such as a high saturated fat intake are thought to be causative. Rarely, the outer rim of the prostate may undergo cancerous change, detectable with blood and ultra-sound measurements, accompanied by biopsy if necessary. These changes my be aggravated by testosterone replacement, possibly due to increased conversion to oestradiol. Subtle changes in mental function and mood are often described – reduced memory, alertness and well-being-as oestrogen/testosterone receptors are widely present throughout the body including the brain.

Less Testosterone As Men Age

As they age, all men produce less testosterone. There is an accompanying enlargement of the prostate gland with a structural change to cell growth (dysplasia) which in a small proportion of men may ultimately become cancerous. Interestingly, the prostate stromal cells are equivalent in men to the endometrial lining cells of the uterus in women and it is now thought that precancerous changes occurring in the endometrium of women have a parallel in the prostatic changes occurring in men.

Prostate Cancer

You should routinely screen for the early changes associated with prostate cancer which are often asymptomatic, but which today represent 15% of all male cancers. Fortunately many prostate cancers remain relatively inactive and are only detected at autopsy following death from other causes.

Blood or saliva tests indicate reduced or cyclical changes of testosterone and other androgens including DHEA, oestrogens and thyroid hormone, as well as secondary changes to lipids, prostate chemistry and blood sugar leading to insulin resistance and diabetes.

Various forms of testosterone are available and may be given as a tablet by mouth, as cream or gel to rub on the skin, as a daily patch on the skin or may be implanted under the skin every 3 to 6 months. The choice of treatment depends on individual preference and efficacy.

Estrogen is a generic term which refers to a number of related substances in the body which have similar action. The main natural estrogen in humans is estradial and weaker oestrogens are estriol and progesterone.

I’m a sex enthusiast, published fantasy writer and the editing director of Brewin’ After Dark. I write about topics surrounding sexual health. Thanks for reading and add me on Twitter!

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